SHANGHAI, China – November 14, 2025 – MediumBank (Shanghai MediumBank Biotechnology Co., Ltd.) announced the official launch of its new GMP-grade liquid media automatic filling production line. This advanced automated platform represents a significant upgrade in production scale, efficiency, quality control, and supply reliability, reinforcing the company's commitment to providing consistent and high-quality core materials to the global biopharmaceutical industry.
The new line is designed to deliver operational certainty through six core advantages:
1. Scalable Capacity for Stable Supply
With single-batch production capacity reaching 2,000 liters, MediumBank has substantially enhanced its large-scale delivery capability. This supports customers throughout the product lifecycle, from clinical development to commercial manufacturing, ensuring a secure and reliable supply chain.
2. Fully Automated Process for Enhanced Efficiency
The automated filling system increases production efficiency by up to 200%, achieving a peak filling speed of 600 bottles per hour. This enables shorter lead times and supports continuous, large-volume production.
3. High-Precision In-Line Weight Control
Integrated Mettler in-process weighing technology, with an accuracy of 0.5‰, ensures strict control of fill volume per container. This provides a solid foundation for process reproducibility and product consistency.
4. Real-Time Environmental Monitoring
The system features continuous online pH monitoring and real-time tracking of critical cleanroom parameters—including airborne particles, microbial counts, and airflow velocity—ensuring consistent adherence to high cleanliness standards.
5. Advanced Cleanroom and Single-Use System Design
Operating within a high-grade cleanroom with dynamic environmental monitoring, the line systematically reduces risks of microbial and particulate contamination. The use of single-use mixing and storage bags during liquid preparation further minimizes cross-contamination and operational variability.
6. Multi-Specification Flexibility
The line supports high-precision automatic filling across four common bottle sizes—125ml, 250ml, 500ml, and 1000ml—providing flexibility to meet needs from process development and pilot-scale to commercial production.
The commissioning of this 2,000L GMP automatic filling line marks a key step in MediumBank's journey toward world-class capabilities in the scalable and automated manufacturing of bioprocessing materials. Moving forward, MediumBank will continue to advance its expertise in upstream biomanufacturing, delivering reliable products and services as a strategic partner to biopharmaceutical companies worldwide.
